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Warfarin ↑↓ Warfarin Warfarin is a mixture of enantiomers which are metabolized by different cytochromes
If clinically appropriate, patients on warfarin should be monitored for signs of increased bleeding/bruising and INR
Dec
If a drug is not listed below, it cannot be assumed to be safe to co-administer
Nirmatrelvir/ritonavir use Changes in the color or temperature of the skin
Outpatients with COVID-19 who are receiving warfarin and are in isolation and unable to have international normalized ratio monitoring may be candidates for switching to direct oral anticoagulant therapy
Rosuvastatin causes warfarin to stay in the body longer
Always consult your healthcare provider before starting or stopping any medication
5mg twice daily, respectively, for the 5-day duration of the Paxlovid™ • A Major Drug Interaction exists between Paxlovid and Seroquel
A new study reviews what is known about such interactions and treatment options that can help These classifications are only a guideline
Opioids: fentanyl, oxycodone, pethidine These classifications are only a guideline
Moderate Paxlovid can interact with other medicines causing severe or life-threatening side effects or death
The relevance of a particular drug interaction to a specific individual is difficult to determine
Revisit the full guidelines to evaluate their place in therapy If patient is on 5mg BID START Paxlovid and DECREASE the dose of Apixaban to 2
You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications
Applies to: metformin and Paxlovid (nirmatrelvir / ritonavir) Ritonavir may interfere with blood glucose control and reduce the effectiveness of metFORMIN and other diabetic medications
More on Warfarin (Coumadin) interactions 7 Common Paxlovid Interactions You Should Know About (Plus Other Medications to Avoid) The COVID-19 pill Paxlovid may